Our lab studies how innate and adaptive immunity is elicited against pathogens that enter the body via mucosal surfaces. Although mucosal surfaces are a common portal of pathogen entry, we know very little about the host pathogen interactions that result in protective immunity when pathogens enter the body through the genital tract. A better understanding of how robust immunological memory, rather than immune pathology, is initiated and maintained in the genital tract will pave the way for developing vaccines and therapeutics against sexually transmitted pathogens, such as HIV.